Articles Posted in Pradaxa

Patients with a serious medical condition known as atrial fibrillation, also known as “Afib,” a type of irregular heartbeat, are generally required to take a prescription blood thinner or oral anticoagulant medication.  Blood thinners have been on the market for decades, and the most popular one is Warfarin, invented in late 1940s and approved for use in the U.S. in 1954.  Pradaxa is a newer type of oral anticoagulant that can lead to serious and irreversible damage, and the company failed to warn of these dangers.

Products Liability cases BostonWarfarin was originally sold under the brand name Coumadin but has been a relatively lost cost generic for many years. While it is generally safe and effective, it can lead to internal bleeding if the dosage is not correct.  These risks can be curtailed by having routine blood work to determine how the drug is working and avoiding certain foods. If there is an adverse event, doctors are able to quickly reverse the side effects with the use of an antidote. Continue reading

Sometimes a drug is used by itself, and sometimes a drug is used as one drug in a multiple drug combination used together to treat a single condition or a series of related conditions.  This is commonly referred to as a drug combo or drug cocktail in some cases, such as with HIV drugs.

greenpillsPradaxa is a member of a class of drugs known as New Oral Anticoagulants (NOACs) and is used, among other things, to treat a serious medical condition known as atrial fibrillation (Afib).  As we have heard former Saturday Night Live actor tell us on the commercials for Xarelto, Afib is a condition identified as an irregular heartbeat not caused by a heart valve defect. Continue reading

Pharmaceutical industry experts have been buzzing recently about the U.S. Food & Drug Administration’s rejection of approval for Xarelto. Specifically, the decision is being lauded by Boehringer Ingelheim, the makers of Pradaxa, according to a recent news feature from FiercePharma.

greenpillsFirst, let’s look at what these two drugs do.  Xarelto and Pradaxa and competitors (along with Eliquis and Savaysa) are in the big money market of New Oral Anticoagulants (NOACs).  This new class of drugs is designed to treat patients who suffer from various potentially deadly clotting disorders that are not caused by a heart valve defect.  Patients who suffer from one of these medical conditions such as atrial fibrillation (Afib) must take a blood thinner or anti-clotting agent to prevent dangerous clots from forming, which may result in a painful death. Continue reading

Patients who suffer from a serious medical condition must take a blood thinner or anticlotting agent to prevent the formation of blood clots that can be deadly.  Patients who suffer from deep vein thrombosis (DVT) and various other conditions need to take these medications to prevent potentially deadly medical conditions from occurring.

whitepillsBlood clotting is an important bodily function.  It is a reaction in the body to stop bleeding.  This can be from internal bleeding or external bleeding, such as when a person gets a cut on his or finger.  People who suffer hemophilia do not clot normally, and this is why even a small cut can lead to serious blood loss.  Continue reading

Atrial Fibrillation (Afib) is a serious medical condition that affects about one in ten Americans over the age of 65.  If someone suffers from atrial fibrillation, which is defined as an irregular heartbeat not associated with a heart valve defect, they will experience what doctors call “bouts” of the condition.

surgery1When a person has a bout of atrial fibrillation, the normal rhythm of the heart that pumps blood throughout the body will stop, and there will be a flutter in the heart that is not effective at pumping blood.  At this point, the patient will typically have symptoms such as a very fast heartbeat, shortness of breath, and dizziness.  While these symptoms can be uncomfortable and dangerous, the real reason people fear Afib is because it can quickly lead to a stroke when the brain is deprived of blood. Continue reading

Many people have seen the recent advertising campaign for Xifaxan, which features what can only be described as an anthropomorphic intestine with a happy face as part of their new commercials.   This is similar to Lunesta using a magical butterfly.  Now the makers of Pradaxa using animated red goldfish to sell their drug.

betta-fish-series-5-1402154Now, recent news feature from BioPharmaDive, discusses how the United States Food and Drug Administration (FDA), is beginning to look into whether this may lead potential drug users into not taking risks seriously because they are being presented with a lovable cartoon character when being told about the risks.

This is of course in addition to the fact that they have a very soothing voice describing serious and possibly deadly medical conditions in way that almost makes them sound like good things. Continue reading

A recent article from Tech Times discusses the effects of a new reversal agent for the drug Pradaxa on patients suffering from a brain hemorrhage.  It is important to note these are brain hemorrhages caused by the drug Pradaxa, which is a relatively new type of anticoagulant medication.

test-tubes-1-1416029-mWhen patients take Pradaxa, we now know there is a significant risk they they will develop a serious internal bleeding disorder than includes possible intracranial bleeding, which is also known as brain hemorrhage.  There is no known way to determine which patients will develop the serious bleeding disorder, as risk factors are not known in the event that there are any.  Continue reading

Pradaxa is a medication used to reduce the risk of serious clotting disorder in patients who suffer from a potentially serious medical condition known as atrial fibrillation (Afib). Afib patients are at higher risk for forming large blood clots deep within the veins on their legs and other extremities.   These blood clots can form in the legs and then break lose and travel through a patient’s circulatory system, which is another deadly medical condition, know as Deep Vein Thrombosis (DVT).

perscription-drugs-2-1160103-mWhen a DVT clot travels through the circulatory system, it can become lodged in the lungs and tear a hole known as a pulmonary embolism (PE) or block the blood to the brain, causing a stroke. To reduce this risk, patients need either a traditional blood thinner like warfarin (Coumadin) or one of the new anticoagulants like Pradaxa, Eliquis, Xarelto, or Savaysa. Continue reading

According to a recent news article from the Washington Post, a federal watch group reports the United States Food and Drug Administration (FDA) exercised “lax” judgment and made “questionable” decisions to be accommodating to the pharmaceutical maker Boehringer Ingelheim when reviewing its application for the anticlotting medication known as Pradaxa.

pillsSome of the specific claims were that FDA set loose safety standards for use during the drug company’s human clinical trials for Pradaxa and also that FDA did not require manufacturer to provide a complete and appropriate warning to prospective patients about the health risks of Pradaxa. Continue reading

Pradaxa, like Xarelto and Eliquis have taken the blood thinner/anticoagulant market by storm in recent years as an alternative to the tried and true blood thinner Warfarin (Coumadin). These drugs were designed to treat patients with an irregular heartbeat condition known as atrial fibrillation (Afib).

untitled-1238929-mAfib patients are at a high risk of developing large blood clots, which can form within the veins deep within the legs. This is a serious and potentially deadly medical condition known as deep vein thrombosis (DVT). The clots can break free from the veins in which they formed and travel through the circulatory system to the lungs where they can cause a hole known as a pulmonary embolism (PE). They clots can also block blood flow to the brain resulting in a stroke. Continue reading